Being a nurse includes down-sides like... Long Shifts and Overtime: Nurses often work 12-hour shifts, and may work extra shifts to earn more money, leading to fatigue and burnout. Physical Strain: The job requires standing for long periods, lifting patients, and moving equipment, which can lead to physical strain, particularly in the back and shoulders. Exposure to Illness and Bodily Fluids: Nurses are constantly exposed to germs, viruses, and bodily fluids, increasing their risk of contracting diseases. Workplace Injuries: Nurses are at risk of workplace injuries, such as slips, trips, and falls, and needle stick injuries.